Laboratory of Drug-Toxicology
Coordinator: Eugenia Gallardo (egallardo@fcsaude.ubi.pt)
The Laboratory of Drug-Toxicology develops its activity in the area of clinical analysis and also in the environmental field – water, food, and others of equal health interest and safeguard public health.
Research
- Dosing of drugs and xenobiotics in biological matrices;
- Evaluation of impurities and characterization of active principles;
- Assay of active substances and contaminants in water and food;
- Evaluation and characterization of plant extracts;
- Evaluation of enzymatic activity in material of biotechnological origin.
Services
- Determination of pesticide residues in water and food;
- Determination of veterinary residues in food;
- Determination of metals and metalloids in water, food and biological fluids;
- Determination of resveratrol in wines;
- Evaluation of impurities and characterization of active principles;
- Determination of enzymatic activity in material of biotechnological origin;
- Dosing of medicaments and xenobiotics in biological matrices;
- Determination of antioxidant activity in plant extracts;
- Determination of polyphenols in plant extracts;
- In vitro toxicity studies;
- Evaluation of pharmacological interactions between drugs and between drugs and plant extracts;
- Toxicology consulting services.
Equipment
- High resolution liquid chromatography coupled to triple quadrupole mass spectrometry (LC-MS / MS)
- Gas chromatography coupled to a Triple Quadrupole mass spectrometer (GC-MS / MS)
- Chromatography gas coupled to flame ionization (GC / FID)
- Gas chromatography coupled mass spectrometry (GC-MS)
- High resolution liquid chromatography coupled to photodiode detector (HPLC / DAD)
- High resolution liquid chromatography coupled to fluorescence detector (HPLC / FLD)
- Vacuum dissecting oven
- UV/VIS spectrophotometry